Single shot of Sputnik V effective against Covid hospitalization & deaths among elderly – Argentine study published by The Lancet

A single dose of the pioneering Russian-made Sputnik V vaccine better protects the elderly against serious Covid-19 infections than a similar regime of certain other leading vaccines, a major new study from Argentina has shown.

The findings were published online by the EClinicalMedicine, which is run by the British peer-reviewed medical journal The Lancet. 

A team of researchers from Argentina analyzed the data of people who self-registered on the online vaccination system of the Buenos Aires Province between December 29, 2020 and March 21, 2021. Overall, they looked at nearly 416,000 people who received a first dose of Sputnik V, including around 40,400 people aged 60-79, who were compared to 39,000 unvaccinated Argentinians. 

The research showed that the vaccine was 78.6% effective at preventing Covid-19 infections, 87.6% effective at reducing hospitalizations and 84.8% effective at preventing deaths of people aged 60-79. The vaccine’s efficacy was consistent across all other groups, the team said. 

For comparison, the scientists summarized eight different studies on the Pfizer-BioNTech, AstraZeneca/Oxford, Moderna and Johnson & Johnson vaccines that included people who received one dose. The reported effectiveness of these four vaccines in preventing symptomatic infection, hospitalizations and deaths ranged from 51-76%, 66.9-91% and 85-91% respectively, they concluded.

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Earlier this year, Russia registered Sputnik Light, a single-shot vaccine that is essentially the first component of Sputnik V, which is administered in two shots. The first doses of Sputnik V arrived in Argentina in December 2020. 

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